Some people have underlying reasons why they are more likely to get a disease than the average person — these are called risk factors. There are a number of potential risk factors for liver cancer. Some risk factors, such as smoking, are lifestyle choices. Others, such as your ethnicity, aren't under your control. Understanding risk factors may improve conversations with a doctor about managing liver cancer risk. Below are some of the most common risk factors; this list is not comprehensive. Talk with your doctor about the risk factors that may be most relevant to you.
Hepatitis B virus (HBV) and hepatitis C virus (HCV)
In the United States, hepatitis B and C are the most common forms of hepatitis and can lead to liver cancer; 862,000 Americans are estimated to be living with HBV, and almost 3 million are estimated to be living with HCV. Most don’t realize that they are infected.
Both of these forms of hepatitis are spread by contact with an infected person’s blood. HBV was often transmitted to an infant from an unknowing mother before HBV vaccines were common. Before 1992, when hepatitis C blood screening became available, hepatitis C could be unknowingly spread by an organ donation or a blood transfusion.
Drinking more than moderate amounts of alcohol
Drinking a lot of alcohol can lead to cirrhosis, which raises the risk for liver cancer. For those who drink alcohol, the Centers for Disease Control and Prevention (CDC) recommends moderate amounts — no more than 1 drink a day for women and 2 for men.
If you are Asian American or Pacific Islander, you may be at higher risk for liver cancer. There are several reasons for this, but hepatitis B is the most common one.
It’s important to note that hepatitis B, which is spread by contact with an infected person’s blood, is different from hepatitis A, which is spread by consuming food or water that has been contaminated with hepatitis A.
There is a higher incidence of hepatitis B in the United States among those born in countries with a high prevalence of chronic hepatitis B, such as countries in Asia and the Pacific Islands.
Asian Americans make up 6% of the total population in the United States but account for 58% of the 862,000 Americans living with chronic hepatitis B.
Your liver’s relationship to hepatitis B virus (HBV)
Chronic hepatitis B can lead to inflammation and damage to the liver, called cirrhosis. A majority of patients with cirrhosis of the liver develop liver cancer.
Asian Americans are 12 times more likely to have chronic hepatitis B and 9 times more likely to die from it, compared to non-Hispanic White persons.
While there is currently no cure for an HBV infection, closely managing it can lower your risk for cirrhosis and liver cancer.
HBV can be passed down from mother to child. If you were born in a country with a high prevalence of HBV or were born in the United States before 1991 when the HBV vaccine became widely available, consider asking your doctor to screen you for HBV. If you were never vaccinated against HBV and have never been tested for the virus, you may be at risk. This is important because it’s possible to be infected and not know it.
Ask your doctor if you should be screened for HBV, and partner with your doctor to manage HBV if you’re positive for the virus.
Asian American liver cancer risk factors — beyond HBV
HBV is a significant risk factor for Asian Americans. But there are others to consider:
Diabetes
According to the Centers for Disease Control and Prevention (CDC), Asian Americans have the highest proportion (50%) of undiagnosed diabetes. Diabetes can increase the risk of liver cancer. It’s important to work closely with your doctor to manage your diabetes. Your doctor may prescribe medication and recommend diet and exercise.
Smoking — quitting may be easier with help
Smoking is linked to an increase in the likelihood of liver cancer. Quitting smoking is an action you can take for your health. For those who smoke, talk to your doctor, as there are many resources to help you quit smoking.
Alcohol — drink moderately
Heavy drinkers are 5 times more likely to develop liver cancer. The Centers for Disease Control and Prevention (CDC) recommends no more than 1 drink a day for women and 2 for men.
Aflatoxin exposure
Some Asians who have immigrated to the United States came from countries where exposure to poisons called aflatoxins is a problem. Exposure to aflatoxins is associated with an increased risk of liver cancer. Aflatoxins are produced by molds that grow on plant products, such as peanuts, grains, or corn.
Consuming meat or dairy products from animals that ate contaminated feed can also lead to exposure. In the United States, there have been no reported outbreaks of human illness as a result of aflatoxins; however, in developing countries, this has been a problem.
Any family can experience disruption and pain when an illness like liver cancer affects one of its own. In the Hispanic population, liver cancer is 2 times more likely to occur, as opposed to in non-Hispanic White persons. Why is this? Here are some of the most common risk factors and some ways you can work with your doctor to manage them.
Diabetes
Hispanics in the United States are twice as likely to develop type 2 diabetes than non-Hispanic whites. What’s more, they are likely to develop it earlier and have more complications. Work with your doctor to manage your diabetes.
Fatty liver disease — the epidemic you’ve never heard of
Non-alcoholic fatty liver disease — or NAFLD for short — is caused by a combination of obesity, diabetes, and other factors. Studies have shown that nearly half of Hispanics live with this condition, which is described as excess fat being stored in the liver.
NAFLD affects an estimated 75 million to 100 million Americans and is the most common cause of chronic liver disease in the country. Hispanic Americans have the highest risk of developing fatty liver disease and having the condition worsen over time, compared to other ethnic groups.
Despite how common this condition is in Hispanics, there are a number of actions that can be taken to lower risk for fatty liver disease and liver cancer. Talk to your doctor to learn more about fatty liver disease and how to manage it.
Obesity — make a plan to maintain a healthy body weight
Being overweight is linked to liver cancer. Work with your family and your doctor to put together a plan you can really commit to, aimed at getting your weight under control.
Diet — embrace a healthier way of eating
Speak to your doctor about making mindful changes to your diet to potentially decrease the severity of fatty liver disease and help reduce risk for diabetes.
Hepatitis C (HCV) — a curable infection
One reason that liver cancer is so high among Hispanics is the number of hepatitis C virus infections. Older Hispanics may have gotten HCV as a result of an organ donation or a blood transfusion. It’s also possible to get HCV through other means, such as sexual contact with an infected person or sharing needles.
No matter how someone might get an HCV infection, it’s important to realize 2 things:
Never share needles
Sharing of contaminated intravenous (IV) needles raises the risk for HCV infection,
and HCV can lead to liver cancer.
Alcohol — drink moderately
Drinking a lot of alcohol can lead to cirrhosis, which raises your risk for liver cancer. For those who drink alcohol, commit to only moderate amounts. The Centers for Disease Control and Prevention (CDC) recommends no more than 1 drink a day for women and 2 for men.
Smoking — quitting may be easier with help
Smoking is linked to an increase in the likelihood of liver cancer. Quitting smoking is an action you can take for your health. For those who smoke, talk to your doctor, as there are many resources to help you quit smoking.
Aflatoxin exposure
Some Hispanics who have immigrated to the United States came from countries where exposure to poisons called aflatoxins is a problem. Exposure to aflatoxins is associated with an increased risk of liver cancer. Aflatoxins are produced by molds that grow on plant products, such as peanuts, grains, or corn.
Consuming meat or dairy products from animals that ate contaminated feed can also lead to exposure. In the United States, there have been no reported outbreaks of human illness as a result of aflatoxins; however, in developing countries, this has been a problem.
It is not known if LENVIMA is safe and effective in children.
It is not known if LENVIMA is safe and effective in children.
LENVIMA may cause serious side effects, including: